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Updated: Oct 30, 2025

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
Overview of the Ultrasound Classification Systems in the Field of Thyroid Cytology
Esther Diana Rossi1, Liron Pantanowitz2, Marco Raffaelli3
1Division of Anatomic Pathology and Histology, Fondazione Policlinico Universitario Agpstino Gemelli, 00168 Rome, Italy.
Abstract:
The increasing application of ultrasound (US) in recent years has led to a greater number of thyroid nodule diagnoses. Consequently, the number of fine needle aspirations performed to evaluate these lesions has increased. Although the majority of thyroid nodules are benign, identifying methods to define specific lesions and tailor risk of malignancy has become vital. Some of the tools employed to stratify thyroid nodule risk include clinical factors, thyroid US findings, and reporting systems for thyroid cytopathology. Establishing high concordance between US features and cytologic diagnoses might help reduce healthcare costs by diminishing unnecessary thyroid procedures and treatment. This review aims to review radiology US classification systems that influence the practice of thyroid cytology.
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