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Gender Differences in the Medical Treatment of Peripheral Artery Disease

Damien Lanéelle1,2, Gabriella Sauvet3, Jérôme Guillaumat1

  • 1Vascular Medicine Unit, Centre Hospitalier Universitaire de Caen Normandie, 14000 Caen, France.

Journal of Clinical Medicine
|July 2, 2021
PubMed

Insights

Optimal medical treatment for peripheral arterial disease is underprescribed, particularly for women. This study highlights disparities in care, emphasizing the need for improved management strategies for female patients with this condition.

Area of Science:

  • Cardiovascular Medicine
  • Public Health
  • General Practice

Background:

  • Peripheral arterial disease (PAD) is a significant condition associated with high cardiovascular risks.
  • Female patients with PAD are frequently undertreated compared to their male counterparts.
  • Understanding treatment disparities is crucial for improving patient outcomes.

Purpose of the Study:

  • To compare the prescription rates of optimal medical treatment (OMT) for PAD between women and men in primary healthcare settings.
  • To identify potential gender-based differences in the management of peripheral arterial disease.

Main Methods:

  • Observational retrospective study utilizing data from general practitioner offices in Brittany, France.
  • Analysis of treatment patterns in 100 patients diagnosed with peripheral arterial disease.
  • Comparison of OMT prescription rates, including antiplatelet therapy, statins, and renin-angiotensin-aldosterone system inhibitors, between genders.

Main Results:

  • Women (24%) received OMT less frequently than men (29.2% vs. 53.9%, p=0.038), especially those over 75.
  • While antiplatelet therapy was universally prescribed, statin use was lower in women (70.8%) than men (85.5%).
  • Renin-angiotensin-aldosterone system inhibitor prescription was suboptimal in both genders (41.7% women vs. 61.9% men).

Conclusions:

  • Optimal medical treatment for peripheral arterial disease is inadequately prescribed in this French region.
  • Significant undertreatment of PAD, particularly in women, was observed in primary care.
  • Further research and interventions are needed to address gender disparities in PAD management.
Abstract

Keywords:
gender differencesoptimal medical treatmentperipheral arterial disease

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