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Updated: Oct 30, 2025

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Microbe-Mediated Biosynthesis of Nanoparticles: Applications and Future Prospects
Bhupendra Koul1, Anil Kumar Poonia2, Dhananjay Yadav3
1School of Bioengineering and Biosciences, Lovely Professional University, Phagwara 144411, Punjab, India.
Microbial biosynthesis offers a faster, safer, and eco-friendly approach to creating nanoparticles (NPs) with tailored properties for diverse applications in medicine, agriculture, and industry.
Area of Science:
- Nanotechnology and Nanoscience
- Microbiology and Biotechnology
Background:
- Nanotechnology utilizes nano-sized particles (~100 nm) with high surface-to-volume ratios, enabling modulation of material properties.
- Nanoparticles (NPs) possess size and shape-dependent characteristics crucial for applications in pharmacy, diagnostics, energy, electronics, and agriculture.
Purpose of the Study:
- To review strategies for synthesizing nanoparticles using microbial cells.
- To explore the applications of microbially synthesized NPs in bioremediation, agriculture, medicine, and diagnostics.
- To discuss the future prospects of microbial nanotechnology.
Main Methods:
- Exploration of various microbes (bacteria, fungi, algae, viruses) for intracellular and extracellular NP synthesis.
- Utilizing microbial machinery for the biosynthesis of metal, metal oxide, and other NPs.
- Investigating genetic engineering to enhance microbial NP synthesis capabilities.
Main Results:
- Microbial biosynthesis presents a quicker, safer, and more environmentally friendly alternative to traditional NP synthesis methods.
- Certain microbes can fabricate unique nanomaterials like exopolysaccharides, nanocellulose, nanoplates, and nanowires.
- Microbial synthesis offers a promising route for producing NPs with desired size, structure, and morphology.
Conclusions:
- Microbial nanotechnology is a unique and promising field with significant potential.
- The review highlights diverse strategies and applications of microbially synthesized NPs.
- Future research should focus on optimizing microbial synthesis and exploring novel applications.
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