In Vitro Fecal Fermentation Patterns of Arabinoxylan from Rice Bran on Fecal Microbiota from Normal-Weight and...

Area of Science:

• Microbiology
• Nutrition Science
• Gastroenterology

Background:

• Arabinoxylan (AX) is a key fiber in cereal grains like rice.
• Dietary AX shows potential prebiotic effects, influencing gut health, particularly in obesity.
• Understanding AX's impact on gut microbiota and metabolites is crucial for health interventions.

Purpose of the Study:

• To investigate the effects of soluble rice bran arabinoxylan (AX) on human gut microbiota composition.
• To analyze short-chain fatty acid (SCFA) production patterns in response to rice bran AX.
• To compare these effects between normal-weight and overweight/obese individuals.

Main Methods:

• In vitro fecal fermentation using soluble AX isolated from rice bran fiber.
• Analysis of gut microbiota phylogenetic composition.
• Quantification of short-chain fatty acid (SCFA) production.

Main Results:

• Rice bran AX significantly altered gut microbiota composition in both weight groups.
• Key increases observed in *Collinsella*, *Blautia*, and *Bifidobacterium*.
• Significant increases in total and individual SCFAs were noted (p < 0.05).

Conclusions:

• Rice bran AX demonstrates prebiotic properties by modulating gut microbiota.
• AX consumption may lead to beneficial changes in SCFA production.
• These findings suggest rice bran AX could positively impact gut health in obesity.