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Related Concept Videos

Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

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The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
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Related Experiment Video

Updated: Oct 30, 2025

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
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Selenium Nanomaterials to Combat Antimicrobial Resistance.

Linh B Truong1, David Medina-Cruz1, Ebrahim Mostafavi2,3

  • 1Department of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.

Molecules (Basel, Switzerland)
|July 2, 2021
PubMed
Summary

Selenium nanoparticles (SeNPs) show promise for treating infections and combating antimicrobial resistance (AMR). Both traditional and green synthesis methods offer unique advantages, though clinical translation requires further safety and regulatory evaluation.

Keywords:
antimicrobialgreen nanotechnologynanoparticles (NPs)selenium nanomaterials (SeNMs)

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Area of Science:

  • Nanotechnology
  • Materials Science
  • Microbiology

Background:

  • Antimicrobial resistance (AMR) is a growing global health crisis, rendering current treatments less effective.
  • Developing new antimicrobial agents is costly, slow, and faces challenges in clinical translation.
  • Nanomaterials offer a promising alternative for effective infection treatment.

Purpose of the Study:

  • To review the synthesis and antimicrobial potential of selenium nanoparticles (SeNPs).
  • To compare traditional and biogenic synthesis approaches for SeNPs.
  • To discuss the challenges and future prospects of SeNPs in combating AMR.

Main Methods:

  • Review of recent literature on SeNP synthesis and antimicrobial applications.
  • Comparison of physiochemical and biogenic (green) synthesis methods for SeNPs.
  • Analysis of SeNPs' efficacy against various pathogens.

Main Results:

  • Both physiochemical and biogenic synthesis methods yield effective SeNPs.
  • Biogenic synthesis is highlighted as eco-friendly, cost-effective, and versatile.
  • SeNPs demonstrate significant potential as antimicrobial agents.

Conclusions:

  • Selenium nanoparticles (SeNPs) are a promising therapeutic strategy against resistant infections.
  • Further research is needed to address in vivo safety and regulatory hurdles for clinical application.
  • SeNPs represent a valuable tool in the fight against the antimicrobial resistance crisis.