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Early Deaths after Arterial Ischemic Stroke in Pediatric Patients: Incidence and Risk Factors

Ilona Kopyta1, Agnieszka Cebula1, Beata Sarecka-Hujar2

  • 1Department of Paediatric Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia in Katowice, Medykow Str 16, 40-752 Katowice, Poland.

Children (Basel, Switzerland)
|July 2, 2021
PubMed

Insights

Pediatric arterial ischemic stroke (AIS) mortality has declined, but early death risk factors remain unclear. Understanding these factors is crucial for prognosis and timely patient supervision in childhood stroke cases.

Area of Science:

  • Neurology
  • Pediatrics
  • Public Health

Background:

  • Cerebrovascular diseases are a leading cause of death in developed countries for both pediatric and adult populations.
  • Arterial ischemic stroke (AIS) in children has a variable mortality rate, ranging from 1% to nearly 32% in different studies.
  • While pediatric stroke mortality shows a declining trend, significant variability exists due to factors like healthcare access, age, ethnicity, and stroke etiology.

Purpose of the Study:

  • To analyze and discuss current literature on the incidence of early death in pediatric stroke.
  • To identify and discuss risk factors associated with early mortality in children experiencing stroke.

Main Methods:

  • Systematic review of existing literature on pediatric stroke outcomes.
  • Analysis of reported incidence of early death in pediatric arterial ischemic stroke (AIS).
  • Identification and synthesis of risk factors for early mortality based on published pediatric stroke case series.

Main Results:

  • The prevalence of fatal outcomes in pediatric AIS varies widely across studies.
  • A general trend of decreasing mortality rates in childhood stroke has been observed.
  • Early death risk factors in pediatric stroke are not well-established, often derived from small patient cohorts.

Conclusions:

  • Further research is needed to fully understand the drivers of variability in pediatric stroke mortality.
  • Identifying early risk factors for death in pediatric stroke is critical for improving patient prognosis.
  • Enhanced understanding of these factors can aid in the early selection of pediatric stroke patients requiring intensive monitoring and care.

Keywords:
arterial ischemic strokechildrendeathmortalityoutcome

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