Assessment of perioperative risk in the patient with diabetes mellitus

C R MacKenzie1, M E Charlson

  • 1Department of Medicine, Cornell University Medical College, New York.

Surgery, Gynecology & Obstetrics
|October 1, 1988
PubMed

Insights

Preoperative clinical factors, not diabetes severity or glucose control, predict surgical complications in diabetic patients. Identifying these characteristics helps manage risks for better patient outcomes.

Area of Science:

  • Cardiology
  • Endocrinology
  • Surgery

Background:

  • Diabetes mellitus (DM) is a prevalent condition associated with increased surgical risks.
  • Identifying patients with DM at higher risk for postoperative complications is crucial for effective perioperative management.

Purpose of the Study:

  • To identify preoperative clinical characteristics that predict serious postoperative complications in patients with diabetes mellitus undergoing surgery.

Main Methods:

  • An inception cohort of diabetic patients undergoing surgical procedures was examined.
  • Preoperative clinical data, including comorbidities and end-organ disease, were analyzed.
  • Postoperative cardiac morbidity, death, and non-cardiac complications were assessed.

Main Results:

  • Pre-existing cardiac disease (congestive heart failure, valvular heart disease) predicted serious cardiac morbidity and death.
  • Diabetic end-organ disease, cardiac conditions, and peripheral vascular disease with infection increased non-cardiac complication risk.
  • Patients without these conditions had a low rate (4%) of serious non-cardiac complications.

Conclusions:

  • Preoperative clinical characteristics, such as specific comorbidities and end-organ damage, reliably predict surgical complications in diabetic patients.
  • Neither diabetes severity nor perioperative glucose control influenced postoperative morbidity or mortality.
  • Risk stratification based on identifiable preoperative factors is key for managing surgical patients with diabetes.

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...