Post-Operative All-Cause Mortality in Elderly Patients Undergoing Abdominal Emergency Surgery: Role of Charlson

Fabio Fabbian1,2, Alfredo De Giorgi2, Silvia Ferro3,4

  • 1Department of Medical Sciences, University of Ferrara, 44121 Ferrara, Italy.

Insights

The Charlson Comorbidity Index (CCI) can predict mortality in elderly patients undergoing emergency abdominal surgery (EAS). A CCI score of 4 or higher significantly increases the risk of death, aiding in preoperative risk assessment.

Area of Science:

  • Geriatric Surgery
  • Surgical Outcomes Research
  • Mortality Prediction Models

Background:

  • The Charlson Comorbidity Index (CCI) is debated for predicting mortality in surgical patients.
  • Elderly patients undergoing emergency abdominal surgery (EAS) require accurate risk stratification.

Purpose of the Study:

  • To evaluate the Charlson Comorbidity Index (CCI) for predicting all-cause mortality in elderly patients (≥65 years) undergoing EAS.
  • To assess the independent predictive value of CCI in this patient cohort.

Main Methods:

  • Retrospective single-center study of 197 elderly patients undergoing EAS from 2017-2019.
  • CCI calculated using ICD-9-CM codes; all-cause death was the primary outcome during follow-up.
  • Cox regression analysis adjusted for age and sex.

Main Results:

  • Overall mortality was 23.8%. Open surgery had higher mortality (74%) than laparoscopic (26%).
  • Mean CCI was 4.98. Patients with CCI ≥ 4 had lower survival.
  • CCI (HR 1.132) and open surgery (HR 10.298) independently predicted all-cause death.

Conclusions:

  • CCI is a valuable tool for preoperative risk stratification in elderly patients undergoing EAS.
  • A CCI score of 4 or higher is associated with increased all-cause mortality, independent of age.

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