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Updated: Oct 30, 2025

An Enrichment Method for Small Extracellular Vesicles Derived from Liver Cancer Tissue
Published on: February 3, 2023
Interplay between Hypoxia and Extracellular Vesicles in Cancer and Inflammation
Marta Venturella1,2, Mattia Criscuoli1, Fabio Carraro3
1Exosomics SpA, Strada del Petriccio e Belriguardo 35, 53100 Siena, Italy.
Abstract:
Hypoxia is a severe stress condition often observed in cancer and chronically inflamed cells and tissues. Extracellular vesicles play pivotal roles in these pathological processes and carry biomolecules that can be detected in many biofluids and may be exploited for diagnostic purposes. Several studies report the effects of hypoxia on extracellular vesicles' release, molecular content, and biological functions in disease. This review summarizes the most recent findings in this field, highlighting the areas that warrant further investigation.
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