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[Drug-induced hepatitis after dihydralazine treatment with fatal consequences]
G Machnik1, A Bergert, J Justus
1Institut für Pathologische Anatomie, Friedrich-Schiller-Universität Jena.
Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie
|January 1, 1988
Abstract:
Adverse drug side effects of the antihypertensive substance dihydralazine have been increasingly observed in recent years. Damage is concentrated on the liver and is characterized by drug-induced hepatitis with confluent necrosis. Three cases (60 year old woman, 79 year old woman, 61 year old man) with lethal course after antihypertensive treatment, using dihydralazine are reported in this paper.