Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

9.1K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
9.1K
Functional Brain Systems: Limbic System01:15

Functional Brain Systems: Limbic System

4.6K
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
4.6K
Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

3.1K
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
3.1K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

1.3K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
1.3K
Integration of Synaptic Events01:28

Integration of Synaptic Events

2.6K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
2.6K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

1.5K
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes From the Multicenter ACCRU-LY-1804/CARiBOU TRIAL (Cytarabine, Acalabrutinib and Rituximab Integrated With Bortezomib-Based Outpatient Therapy) in 1st Line Mantle Cell Lymphoma.

American journal of hematology·2026
Same author

Physical, cognitive, and psychosocial fatigue are differently related to cortical complexity of superior temporal and frontal brain regions in Crohn's disease.

Frontiers in neuroimaging·2026
Same author

Arm Pain After a Fall: The Use of POCUS to Evaluate Fractures in the Emergency Department.

Advanced emergency nursing journal·2026
Same author

White Matter Damage in Multiple Sclerosis Disproportionately Targets Default Mode, Executive Control, and Salience Networks.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2026
Same author

Early Outcomes of an Extended Postpartum Hypertension Program: Care Beyond Delivery.

JACC. Case reports·2026
Same author

Real-world evidence for pembrolizumab gemcitabine vinorelbine and liposomal doxorubicin in classical Hodgkin lymphoma.

Blood advances·2026

Related Experiment Video

Updated: Oct 30, 2025

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

12.4K

The Relationship Between Functional Connectivity and Interoceptive Sensibility.

Stephen D Smith1, Catherine Nadeau1, Megan Sorokopud-Jones2

  • 1Department of Psychology, University of Winnipeg, Winnipeg, Canada.

Brain Connectivity
|July 2, 2021
PubMed
Summary
This summary is machine-generated.

Individual differences in interoceptive sensibility, or self-reported awareness of bodily signals, are linked to distinct brain connectivity patterns. These neural correlates of sensibility differ from those underlying interoceptive accuracy, highlighting unique brain networks for subjective bodily awareness.

Keywords:
Multidimensional Assessment of Interoceptive Awarenessfunctional connectivityinteroceptioninteroceptive sensibilityresting-state fMRI

More Related Videos

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.4K
Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
06:04

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: January 17, 2025

889

Related Experiment Videos

Last Updated: Oct 30, 2025

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time
07:12

Using Informational Connectivity to Measure the Synchronous Emergence of fMRI Multi-voxel Information Across Time

Published on: July 1, 2014

12.4K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.4K
Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling
06:04

Functional Near-Infrared Spectroscopy Hyperscanning Study in Psychological Counseling

Published on: January 17, 2025

889

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Psychology

Background:

  • Interoceptive signals from the body (heartbeat, respiration, gut) continuously inform the brain, influencing cognition and emotion.
  • Interoceptive accuracy (detecting signals) and interoceptive sensibility (beliefs about detection) are distinct constructs.
  • Neural basis of interoceptive accuracy is known, but the brain areas underlying interoceptive sensibility are less understood.

Purpose of the Study:

  • To investigate the neural correlates of interoceptive sensibility using resting-state functional magnetic resonance imaging (rs-fMRI).
  • To compare the brain regions associated with interoceptive sensibility versus interoceptive accuracy.

Main Methods:

  • Twenty-eight healthy participants completed the Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire.
  • Resting-state fMRI data were acquired for 7 minutes.
  • Region-of-interest and independent-component analyses examined correlations between MAIA scores and functional connectivity.

Main Results:

  • Interoceptive sensibility showed a negative correlation with functional connectivity in visual regions.
  • The cerebellar resting-state network positively correlated with two MAIA subscales, suggesting its role in interoceptive functions.
  • The insula, crucial for interoceptive accuracy, did not show correlations with interoceptive sensibility scores.

Conclusions:

  • Brain areas associated with individual differences in interoceptive sensibility largely differ from those involved in interoceptive accuracy.
  • Subjective beliefs about interoceptive abilities (sensibility) involve distinct neural structures, including visual regions and the cerebellum.
  • This study differentiates the neural underpinnings of objective signal detection versus subjective awareness of bodily states.