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Exercise Oscillatory Ventilation in Hypertrophic Cardiomyopathy.
Stefanos G Sakellaropoulos1, Aaron L Baggish1, Michael A Fifer1
1Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Current Problems in Cardiology
|July 2, 2021
Summary
Exercise oscillatory ventilation (EOV) is uncommon in hypertrophic cardiomyopathy (HCM) patients. EOV may indicate more severe HCM, linked to heart failure and reduced exercise capacity.
Area of Science:
- Cardiology
- Pulmonary Medicine
- Exercise Physiology
Background:
- Hypertrophic cardiomyopathy (HCM) is a significant cause of heart failure.
- Exercise oscillatory ventilation (EOV) is a complex breathing pattern observed during exercise.
Purpose of the Study:
- To determine the prevalence of EOV in HCM patients.
- To identify clinical factors associated with EOV in this population.
Main Methods:
- Retrospective single-center study.
- Analysis of cardiopulmonary exercise testing data from 36 consecutive HCM patients.
Main Results:
- EOV was present in 5.6% of HCM patients (2 out of 36).
- Patients with EOV had lower peak oxygen consumption (VO2 ≤ 9.1 ml/kg/min), larger left atrial size, and were more likely to have NYHA Class 3 heart failure.
- One of two patients with abnormal blood pressure response to exercise had EOV.
Conclusions:
- EOV is an infrequent finding in HCM.
- EOV may serve as a marker for increased disease severity in HCM, correlating with overt heart failure, left atrial enlargement, and diminished peak VO2.
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