Related Experiment Video
Updated: Oct 30, 2025

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
COVID-19 diagnosis in a patient with critical limb ischemia: complications and clinical outcomes
Rafael de Athayde Soares1, Rafael Salem Vedovello1, Samanta Christine Guedes de Medeiros1
1Hospital Regional Sul, Serviço de Cirurgia Vascular e Endovascular, São Paulo, SP, Brasil.
Insights
A patient with peripheral artery disease developed severe COVID-19 after endovascular repair. Despite treatment, the patient succumbed to the viral infection, highlighting potential complications in vulnerable populations.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Critical Care Medicine
Background:
- Peripheral artery disease (PAD) management often involves endovascular procedures.
- Diabetic patients with hypertension present complex surgical challenges.
- The emergence of SARS-CoV-2 (COVID-19) poses significant risks to patients with comorbidities.
Abstract:
A 67-year-old male diabetic patient with systemic arterial hypertension was admitted to the emergency department with a necrotic ulcer in the left external malleolus and no palpable popliteal or pedal pulses. Arterial Duplex ultrasound identified femoropopliteal occlusion, with popliteal refilling below the knee and a patent peroneal artery. An endovascular procedure was performed, requiring retrograde access to the popliteal artery to re-establish blood flow and deploy a popliteal stent. Technical success was achieved and the patient underwent debridement of the wound. Two days later, about 48 hours after the operation, the patient began to exhibit respiratory symptoms, with coughing and dyspnea. He immediately underwent a chest CT that identified ground glass opacities, the crazy-paving pattern, and bilateral air bronchogram in the lungs. A reverse transcription - polymerase chain reaction (RT-PCR) test was positive for SARS-Cov-2. The patient was moved to an intensive care unit and put on mechanical ventilation. Both hydroxychloroquine and azithromycin were administered. Despite appropriate treatment, the patient died 4 days after he was diagnosed with COVID-19.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Acute Coronary Syndrome III: Diagnostic Studies
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease IV: Nursing Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

