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Published on: March 16, 2022
Limb ischemia in patients with COVID-19
Julio Cesar Peclat de Oliveira1, Walter Jr Boim Araujo2, Sergio Quilici Belczak3
1Universidade Federal do Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brasil.
This review details life-threatening blood clots in COVID-19, including vascular damage and thrombosis. It covers coagulation management and anticoagulation strategies for patients with SARS-CoV-2 infection.
Area of Science:
- Cardiovascular Medicine
- Infectious Diseases
- Hematology
Background:
- SARS-CoV-2 infection, or COVID-19, is associated with a significant risk of thromboembolic events.
- Understanding the pathophysiology of these events is crucial for effective patient management.
Purpose of the Study:
- To provide a comprehensive review of life-threatening thromboembolic complications in COVID-19.
- To discuss the vascular and arterial damage, coagulation laboratory management, and anticoagulation strategies.
- To highlight the relationship between COVID-19 and deep venous thrombosis (DVT) and arterial thrombosis.
Main Methods:
- Narrative review of existing literature.
- Inclusion of clinical examples from patient experiences with COVID-19.
Main Results:
- COVID-19 causes physical changes leading to vascular and arterial damage, particularly in the limbs.
- The review emphasizes the link between SARS-CoV-2 infection and both deep venous thrombosis and arterial thrombosis.
- Effective laboratory management of coagulation and appropriate anticoagulation are critical.
Conclusions:
- Thromboembolic events represent a major life-threatening complication of COVID-19.
- Management strategies should address vascular damage, coagulation abnormalities, and anticoagulation.
- Further research and clinical vigilance are necessary to mitigate these risks.
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