Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of the gene cluster for the dithiolopyrrolone antibiotic holomycin in Streptomyces clavuligerus.

Proceedings of the National Academy of Sciences of the United States of America·2010
Same author

Safety evaluation of tea (Camellia sinensis (L.) O. Kuntze) flower extract: assessment of mutagenicity, and acute and subchronic toxicity in rats.

Journal of ethnopharmacology·2010
Same author

Influences of soil properties and leaching on nickel toxicity to barley root elongation.

Ecotoxicology and environmental safety·2010
Same author

Effects of CO2 insufflation on cerebrum during endoscopic thyroidectomy in a porcine model.

Surgical endoscopy·2010
Same author

Plants' use of different nitrogen forms in response to crude oil contamination.

Environmental pollution (Barking, Essex : 1987)·2010
Same author

Overexpression of p35 in Min6 pancreatic beta cells induces a stressed neuron-like apoptosis.

Journal of the neurological sciences·2010

Related Experiment Video

Updated: Oct 30, 2025

Three-Dimensional Motor Nerve Organoid Generation
09:57

Three-Dimensional Motor Nerve Organoid Generation

Published on: September 24, 2020

9.7K

3D printing of functional nerve guide conduits.

Yulan Huang1, Wenbi Wu1, Haofan Liu1

  • 1State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, 610041, China.

Burns & Trauma
|July 2, 2021
PubMed
Summary

3D printing offers advanced fabrication of nerve guide conduits (NGCs) to improve peripheral nerve injury repair. This review explores 3D printing technologies and strategies for creating functional NGCs, enhancing axonal regeneration and myelination.

Keywords:
3D printingFunctionalizationNerve guide conduitsPeripheral nerve repair

More Related Videos

Author Spotlight: Developing Cost-Effective and Durable Ultrasound-Guided 3D-Printed Nerve Block Trainers
08:03

Author Spotlight: Developing Cost-Effective and Durable Ultrasound-Guided 3D-Printed Nerve Block Trainers

Published on: February 9, 2024

2.5K
Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.4K

Related Experiment Videos

Last Updated: Oct 30, 2025

Three-Dimensional Motor Nerve Organoid Generation
09:57

Three-Dimensional Motor Nerve Organoid Generation

Published on: September 24, 2020

9.7K
Author Spotlight: Developing Cost-Effective and Durable Ultrasound-Guided 3D-Printed Nerve Block Trainers
08:03

Author Spotlight: Developing Cost-Effective and Durable Ultrasound-Guided 3D-Printed Nerve Block Trainers

Published on: February 9, 2024

2.5K
Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering
10:17

Preparation and Characterization of Graphene-Based 3D Biohybrid Hydrogel Bioink for Peripheral Neuroengineering

Published on: May 16, 2022

2.4K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Nerve guide conduits (NGCs) are crucial for peripheral nerve injury repair, but their efficacy requires enhancement.
  • Current NGCs often lack the optimal microenvironment for promoting axonal regeneration and myelination.
  • 3D printing technology presents a promising avenue for fabricating advanced NGCs.

Purpose of the Study:

  • To review 3D printing technologies for manufacturing functional NGCs.
  • To summarize strategies for enhancing NGCs for nerve regeneration.
  • To discuss challenges and future prospects in functional NGC development.

Main Methods:

  • Review of existing literature on 3D printing techniques (inkjet, extrusion, stereolithography, indirect printing) for NGC fabrication.
  • Analysis of methods for creating functional NGCs, including architectural design, material selection, and incorporation of biological cues.
  • Discussion of challenges and future directions in the field.

Main Results:

  • 3D printing enables the creation of customized and complex NGC architectures.
  • Strategies like special conduit designs, appropriate biomaterials, and co-printing with biological factors can improve NGC functionality.
  • Various 3D printing methods offer distinct advantages for NGC manufacturing.

Conclusions:

  • 3D printing is a powerful tool for developing next-generation NGCs with improved regenerative potential.
  • Functional NGCs fabricated using 3D printing can significantly enhance axonal elongation and myelination.
  • Further research is needed to overcome challenges and fully realize the clinical potential of 3D printed NGCs.