Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer

Silvia Achilli1, Nathalie Berthet1, Olivier Renaudet1

  • 1Univ. Grenoble Alpes, CNRS DCM UMR 5250 F-38000 Grenoble France nathalie.berthet@univ-grenoble-alpes.fr olivier.renaudet@univ-grenoble-alpes.fr.

Antibody-recruiting molecules (ARMs) are one of the most promising tools to redirect the immune response towards cancer cells. In this review, we aim to highlight the recent advances in the field. We will illustrate the advantages of different ARM approaches and emphasize the importance of a multivalent presentation of the binding units.

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