Related Experiment Video
Updated: Oct 30, 2025
LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation
Published on: January 24, 2025
[Successful treatment of cutaneous leishmaniasis with simulated daylight photodynamic therapy]
Sarah Hobelsberger1, Marie-Paloma Krauß2, Christian Bogdan3
1Klinik und Poliklinik für Dermatologie, Universitätsklinikum Carl Gustav Carus Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland. Sarah.Hobelsberger@uniklinikum-dresden.de.
Abstract:
A 5-year-old Syrian boy , presented with a complex cutaneous leishmaniasis (CL) of the right ankle caused by Leishmania (L.) tropica. The patient received photodynamic therapy (PDT; 6 cycles with application of 5‑aminolevulinic acid and foil occlusion for 3 h). Due to pain during exposure to red light, exposure was continued with simulated daylight (sDL-PDT). The lesion healed with an atrophic scar. Due to fewer side effects and less pain, sDL-PDT seems to be a good therapeutic strategy for CL caused by L. tropica.
