Computer-aided quantitative MSCT measurements may be useful for congenital lung malformations surgical approach...

To examine the association between the MSCT quantitative measurements of congenital lung malformations (CLM) and the selection of surgical approaches (lobectomy vs. lung-sparing surgery).

This retrospective study evaluated CLM surgical cases at our institution from 2016 to 2018. MSCT quantitative measurements were generated by a semi-automated approach: the volume of the lesion (V_lesion), the volume of the lesion-involved lobe (V_lobe), the volume of the lesion-involved lung (V_lung) and the volume of the total lung (V_{total lung}). The proportions of V_lesion to V_lobe (P_lesion/lobe), V_lesion to V_lung (P_lesion/lung), and V_lesion to V _{total lung} (P_{lesion/total lung}) were calculated. We used Logistics regression to examine whether quantitative measurements were associated with the selection of surgical approaches.

151 patients were included (median age at surgery 6 months). 82 patients underwent lung-sparing surgery, and 69 patients underwent lobectomy. V_lesion (OR 1.51, 95% CI 1.09-2.07), P_lesion/lobe (OR 1.78, 95% CI 1.16-2.72), P_lesion/lung (OR 1.63, 95% CI 1.13-2.35), and P_{lesion/total lung} (OR 1.58, 95% CI 1.12-2.22) were positively associated with the selection of lobectomy.

The application of quantified MSCT analysis may provide insight into the quantitative characteristics of CLM, which could be potentially useful for surgical approach selection.