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Detection of immunoglobulin response to COVID-19 vaccination using a novel rapid fingerstick assay
1NOWDiagnostics, Inc., Springdale, AR, USA.
Insights
A new COVID-19 antibody test detects SARS-CoV-2 antibodies from a fingerstick blood sample after vaccination. This rapid test shows antibodies appear early and last for at least six months.
Area of Science:
- Immunology
- Virology
- Diagnostic Assay Development
Background:
- Coronavirus Disease 2019 (COVID-19) is a global pandemic with significant health impacts.
- COVID-19 vaccines are effective in preventing infection and reducing disease severity.
- Monitoring immune response post-vaccination is crucial for understanding vaccine efficacy.
Abstract:
Coronavirus Disease 2019 (COVID-19) emerged as a global pandemic resulting in significant mortality and morbidity. COVID-19 vaccines have been shown to be highly effective in preventing COVID-19 infections and significantly reducing disease severity and mortality. We report on a novel COVID-19 antibody assay using a unique platform to rapidly detect SARS-CoV-2 antibodies with a drop of fingerstick blood in a subject following COVID-19 vaccination. We show early detection of SARS-CoV-2 antibodies post vaccination and persistence of detectable antibodies for at least 6 months. Rapid point of care COVID-19 antibody tests might have a role in assessing the appearance and durability of immune response following COVID-19 vaccination.
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