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Mucormycosis causing massive lower gastrointestinal bleeding: a case report.

Ting-Hsuan Chiang1, Yi-Wei Lee1, Jui-Hsiang Tan2

  • 1School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, ROC.

BMC Gastroenterology
|July 3, 2021
PubMed
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A rare case of gastrointestinal mucormycosis caused massive lower gastrointestinal bleeding in a diabetic patient. Prompt antifungal treatment led to successful recovery, highlighting the importance of early diagnosis in immunocompromised individuals.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Mycology

Background:

  • Lower gastrointestinal bleeding (LGIB) is a common hospital complication.
  • Infectious causes of LGIB are rare but can lead to severe outcomes.
  • Diagnosing rare infectious LGIB preoperatively can be challenging.

Observation:

  • A patient with diabetes and alcohol abuse presented with altered mental status and massive hematochezia.
  • Colonoscopy revealed a transverse colon ulcer with features suggestive of mucormycosis.
  • Biopsy confirmed mucormycosis with characteristic hyphae.

Findings:

  • The patient received 2 months of antifungal therapy.
  • Follow-up colonoscopy showed complete resolution of the ulcer.
  • This case highlights a rare but serious cause of LGIB.
Keywords:
Case reportDiabetic ketoacidosisHematocheziaMucormycosisOpportunistic infection

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Implications:

  • Early diagnosis and treatment of gastrointestinal mucormycosis are crucial.
  • Clinical vigilance for mucormycosis in immunocompromised patients is essential.
  • Prompt antifungal prophylaxis may be warranted in high-suspicion cases.