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Related Concept Videos

Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

1.4K
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
1.4K
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

1.7K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
1.7K
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

168
Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
168
Dysrhythmias VII: Nursing Management of Dysrhythmias01:25

Dysrhythmias VII: Nursing Management of Dysrhythmias

167
Nursing management of dysrhythmias involves the following:AssessmentSubjective Assessment:The initial step involves gathering patient-reported symptoms such as dizziness, palpitations, and chest discomfort. It is crucial to collect a detailed history, including previous heart conditions, current medication use, and lifestyle factors like caffeine and alcohol consumption.Objective Assessment:This involves observing clinical signs such as jugular venous distention, cool and pale skin, and...
167
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

221
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
221
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

511
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
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Related Experiment Video

Updated: Oct 30, 2025

Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus
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Methods for ECG Evaluation of Indicators of Cardiac Risk, and Susceptibility to Aconitine-induced Arrhythmias in Rats Following Status Epilepticus

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Chemotherapy-Induced Arrhythmia - Underrecognized and Undertreated.

Hani Essa1, David J Wright1, Rebecca Dobson1

  • 1Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool Heart & Chest Hospital, UK.

The American Journal of Medicine
|July 3, 2021
PubMed
Summary

Chemotherapy can cause heart rhythm problems like atrial fibrillation and prolonged QTc in cancer patients. Close collaboration between oncologists and cardio-oncologists is crucial for managing these cardiac complications.

Keywords:
ArrhythmiaAtrial fibrillationCardio-oncologyChemotherapyProlonged QTc

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Area of Science:

  • Cardiology
  • Oncology
  • Pharmacology

Background:

  • Cancer is a leading global cause of death.
  • Chemotherapy-induced arrhythmia is a serious complication impacting cancer patient morbidity and mortality.
  • The link between chemotherapy drugs and cardiac arrhythmias is not well understood.

Purpose of the Study:

  • To review the common cardiac arrhythmias in cancer patients undergoing chemotherapy.
  • To discuss the challenges in managing these arrhythmias, including drug interactions and lack of validated risk scores.
  • To highlight the importance of QTc prolongation and its potential severe consequences.

Main Methods:

  • Literature review on chemotherapy-induced arrhythmias.
  • Analysis of common arrhythmia types: atrial fibrillation, ventricular ectopic beats, and QTc prolongation.
  • Discussion of treatment complexities and risk assessment in cancer patients.

Main Results:

  • Atrial fibrillation, ventricular ectopic beats, and QTc prolongation are frequent in cancer patients on chemotherapy.
  • Managing atrial fibrillation is complex due to drug interactions and limited evidence.
  • QTc prolongation by chemotherapeutic agents can lead to torsades de pointes and sudden cardiac death.

Conclusions:

  • Oncologists must collaborate with cardio-oncologists for optimal management of chemotherapy-induced cardiac arrhythmias.
  • Further research is needed to establish clear guidelines for managing these arrhythmias in cancer patients.
  • Risk stratification and anticoagulation decisions require cancer-specific validation.