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Updated: Oct 30, 2025

Ultrasound Imaging-guided Intracardiac Injection to Develop a Mouse Model of Breast Cancer Brain Metastases Followed by Longitudinal MRI
Published on: March 6, 2014
Metastatic involvement of optic nerve in patient with breast and lung neoplasia
F J Valentín-Bravo1, C García-Álvarez1, M Para-Prieto1
1Departamento de Oftalmología, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Abstract:
Metastases are the most common adult intraocular tumors. However, those located in the optic nerve are very uncommon and are usually associated with spread to other locations such as the central nervous system, which darkens the prognosis. There is a case of a 67-year-old woman who reports progressive vision loss in the right eye of 15 days of evolution. The ophthalmological examination shows a relative afferent pupil defect in this eye and a pseudoedema of the papilla with retinal hemorrhages in the fundus. Personal history and characteristics of the optic nerve suggest the diagnosis of metastatic infiltration.

