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Pain in Patients With Chronic Kidney Disease Undergoing Hemodialysis: A Systematic Review
Patrícia Roberta Dos Santos1, Carolina Rodrigues Mendonça1, Janete Capel Hernandes1
1Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal de Goiás, Goiânia, Goiás, Brazil.
Insights
Pain is common in patients with chronic kidney disease (CKD) undergoing hemodialysis (HD), frequently affecting daily life. This systematic review highlights the prevalence and impact of pain in this population.
Area of Science:
- Nephrology
- Pain Management
- Public Health
Background:
- Chronic kidney disease (CKD) affects a significant population, with many patients requiring hemodialysis (HD).
- Pain is a frequently reported symptom in patients with CKD undergoing HD, impacting their quality of life.
Purpose of the Study:
- To assess the prevalence, location, intensity, and effects of pain on daily activities in patients with CKD undergoing HD.
- To synthesize existing evidence on pain experienced by hemodialysis patients.
Main Methods:
- Systematic review of studies published between 2005 and 2020.
- Searched Embase, SciELO, PubMed, and Web of Science databases.
- Included 25 studies involving 98,162 patients.
Main Results:
- High prevalence of pain reported in adult and elderly patients with CKD on HD.
- Most common pain sites include head, back, bones, chest, and limbs.
- Moderate to severe pain frequently impacts daily activities, mobility, mood, sleep, and work.
Conclusions:
- Acute and chronic pain are prevalent in adults and elderly patients undergoing HD.
- Pain significantly interferes with various aspects of everyday life for dialysis patients.
Aims:
To assess the presence of pain, its location, intensity, and effects on the daily activities of patients with chronic kidney disease (CKD) undergoing hemodialysis (HD).
Participants/Subjects:
Patients with chronic kidney disease (CKD) undergoing hemodialysis (HD).
Design:
A systematic review.
Methods:
We carried out search for articles published until December 2020, including publications in Portuguese, English, and Spanish during the past 15 years (2005-2020), using the Embase, SciELO, PubMed, and Web of Science databases. The following information was collected: type of pain, pain treatment, pain assessment instrument, prevalence of pain, location, and influence of pain on quality of life.
Results:
Twenty-five studies were selected for a systematic review. These studies involved a total of 98,162 adult and elderly patients with CKD who were undergoing HD. There was a high prevalence of pain in patients with CKD on HD. The most frequent sites of pain were the head, back, bones, chest, and the upper and lower limbs. The presence of acute, chronic, neuropathic pain, and myalgia was also reported in the studies. In addition, there was a higher frequency of moderate and severe pain, which influenced daily activities, the ability to walk, mood, relationships with other people, sleep, and work in patients on dialysis.
Conclusions:
The analyzed studies suggest that acute and chronic pain is a prevalent complaint in adults and elderly patients undergoing HD. There was a higher frequency of moderate and severe pain in different parts of the body, and pain interfered with everyday activities.
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