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Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides

Marie Flamme1, Steven Hanlon2, Hans Iding2

  • 1Institut Pasteur, Department of Structural Biology and Chemistry, Laboratory for Bioorganic Chemistry of Nucleic Acids, CNRS UMR3523, 28, rue du Docteur Roux, 75724 Paris Cedex 15, France.

Bioorganic & Medicinal Chemistry Letters
|July 4, 2021
PubMed

Keywords:
Locked nucleic acidsModified nucleotidesPhosphorothioatesPolymerase synthesisTerminal deoxynucleotidyl transferase (TdT)

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