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Cardiac effects of botulinal toxin

C Lamanna1, A N el-Hage, J A Vick

  • 1Center for Drug Evaluation and Research, Food and Drug Administration, Washington DC 20204.

Archives Internationales De Pharmacodynamie Et De Therapie
|May 1, 1988
PubMed
Summary

Botulinum toxin type A rapidly caused temporary heart rate and ECG changes in multiple animal models. These cardiac effects suggest a physical interaction mechanism, as they were reversible in intact animals.

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