Related Experiment Video

Updated: Oct 30, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.4K

Diagnostic performance of chest radiography in high COVID-19 prevalence setting: experience from a European reference

Nicola Flor1,2, Lorenzo Saggiante3, Anna Paola Savoldi3

  • 1U.O. di Radiodiagnostica, Ospedale L. Sacco ASST Fatebenefratelli Sacco, Via Giovanni Battista Grassi, 74, 20157, Milan, MI, Italy. nicola.flor@unimi.it.

Emergency Radiology
|July 4, 2021
PubMed

Insights

Chest radiography (CXR) demonstrated 79% sensitivity and 81% specificity for diagnosing COVID-19 pneumonia in symptomatic patients. Expert radiologists achieved higher accuracy than residents, with improved sensitivity for symptom onset over 5 days prior.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonary Medicine

Background:

  • The COVID-19 pandemic necessitated rapid diagnostic strategies.
  • Chest radiography (CXR) is a widely accessible imaging modality.
  • Evaluating CXR's diagnostic performance for COVID-19 is crucial.

Purpose of the Study:

  • To analyze the diagnostic performance of chest radiography (CXR) in patients with suspected coronavirus disease 19 (COVID-19).

Main Methods:

  • Retrospective analysis of 680 patients with suspected COVID-19 who underwent CXR and rRT-PCR.
  • CXR interpretation by an expert radiologist and two residents, blinded to rRT-PCR results.
  • rRT-PCR served as the reference standard for COVID-19 diagnosis.

Main Results:

  • CXR achieved a sensitivity of 79.0% and specificity of 81.2% when interpreted by an expert radiologist.
  • Residents' interpretation yielded lower sensitivity (75.1%) and specificity (57.9%).
  • Sensitivity was higher in patients with symptom onset > 5 days (84.4%) compared to ≤ 5 days (70.7%).

Conclusions:

  • CXR demonstrates valuable sensitivity and specificity for diagnosing COVID-19 pneumonia in symptomatic patients.
  • Expert radiologist interpretation significantly outperformed residents.
  • Further research in lower prevalence settings is warranted.
Abstract

Keywords:
PneumoniaRadiology/radiography

More Related Videos

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.4K
Point-of-Care Lung Ultrasound in Adults: Image Acquisition09:17

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Published on: March 3, 2023

6.7K

Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
606
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
540
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
2.7K
Imaging Studies for Cardiovascular System III: X-Ray01:20

Imaging Studies for Cardiovascular System III: X-Ray

The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
329
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
79
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
519