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Autosomal Dominant Cerebral Small Vessel Disease in HTRA1 Gene Mutation
Rohan R Mahale1, Aakash Agarwal1, Jyothi Gautam1
1Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Annals of Indian Academy of Neurology
|July 5, 2021
Abstract
No abstract available in PubMed .
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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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