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Updated: Oct 30, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Association between periodontitis and vitamin D status: A case-control study.
Abdullah Ali H Alzahrani1, Raed A Alharbi2, Mohammed Sarhan A Alzahrani3
1Dental Health Department, Faculty of Applied Medical Sciences, Albaha University, Albaha, Saudi Arabia.
Periodontitis is linked to low vitamin D levels in Saudi adults. This study found lower serum 25-hydroxyvitamin D (25(OH)D) in individuals with periodontitis, suggesting a significant association.
Area of Science:
- Oral Health
- Endocrinology
- Public Health
Background:
- Periodontitis and vitamin D deficiency are common in Saudi adults.
- The relationship between periodontitis and vitamin D status requires further investigation.
Purpose of the Study:
- To investigate the association between periodontitis and vitamin D status in Saudi adults from the Albaha region.
Main Methods:
- A case-control study involving 123 Saudi adults (60 with periodontitis, 63 controls).
- Data collected via online sociodemographic questionnaire, periodontal examination, and serum 25-hydroxyvitamin D (25(OH)D) level assessment.
- Participants were matched for BMI, age, and sex.
Main Results:
- Mean serum 25(OH)D levels were significantly lower in the periodontitis group (25.03 ± 8.55 ng/ml) compared to the control group (29.19 ± 12.82 ng/ml) (p=0.037).
- Lower odds of periodontitis were associated with each unit increase in serum 25(OH)D level (OR 0.964, 95% CI: 0.931-0.999, p=0.043).
Conclusions:
- Periodontitis is significantly associated with deficient and insufficient vitamin D levels in Saudi adults in the Albaha region.
- Further longitudinal research with larger sample sizes is recommended to validate these findings.
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