Related Experiment Videos
Trisomy 11 in myelodysplasia
R Morgan1, M H Greene, A A Sandberg
1Genetics Center Southwest Biomedical Research Institute, Scottsdale, AZ 85345.
Cancer Genetics and Cytogenetics
|January 1, 1988
Abstract:
A case of pancytopenia with dysplastic changes in the bone marrow with trisomy 11 (+11) as the sole karyotypic anomaly in an adult male is described. The literature on +11, both as a primary (14 cases) and secondary (55 cases) cytogenetic event in hematologic disorders, is summarized and the findings are discussed. There is the possibility that +11 is a nonrandom chromosomal anomaly in some myelodysplastic disorders.