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Intracranial pressure and laboratory parameters in high- and low-risk pregnant women
Daniel da Silveira1, Nícollas Nunes Rabelo2, Mateus Gonçalves de Sena Barbosa2
1Graduate Program of Biomedical Sciences, State University of Ponta Grossa, Ponta Grossa, Paraná, , Brazil.
Background:
Pregnancy can trigger several pathological changes, thus representing a great challenge for gynecology and obstetrics. The objective is to evaluate high- and low-risk pregnant women through Intracranial pressure (ICP) and laboratory parameters.
Methods:
Volunteers clinical and laboratory data were collected from medical records and ICP was monitored through noninvasive method.
Results:
Statistically significant differences were observed between the group of high-risk and low-risk pregnant women for serum levels of alkaline phosphatase (ALP) and US-C-reactive protein (CRP) and a statistically positive association between blood pressure (BP) levels and plasma glucose. About 12.77% of the volunteers presented altered ICP. Higher BP values were encountered with the higher plasma glucose values. All ICP altered volunteers presented altered BP. ALP is among the most effective biochemical markers for assessing the risk of premature birth before 32 weeks of gestation.
Conclusion:
We have observed important changes on BP, serum glucose, US-CRP, and ALP thus indicating higher risk of complications during pregnancy. Even more, some of the volunteers presented altered ICP what could indicate cerebral compliance changes.
