COVID-19 and Cardiomyopathy: A Systematic Review
Fatemeh Omidi1, Bahareh Hajikhani2, Seyyedeh Neda Kazemi3
1Department of Cardiology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Frontiers in Cardiovascular Medicine
|July 5, 2021
Summary
Sudden cardiac death in adolescents is often linked to cardiomyopathies (CMPs). This study found cardiac injury and CMPs are common in COVID-19 patients, highlighting the need for cardiac monitoring.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Cardiomyopathies (CMPs) are a significant cause of sudden adolescent death and heart failure.
- Limited data existed on cardiac complications in COVID-19 patients during the pandemic.
- Investigating the link between COVID-19 and CMPs is crucial for understanding severe outcomes.
Approach:
- A systematic literature search was performed across major databases (PubMed/Medline, Web of Science, Embase) up to August 2020.
- Included 29 articles encompassing 1460 patients diagnosed with COVID-19 and cardiomyopathy.
- Analyzed comorbidities, laboratory findings, and echocardiographic results.
Key Points:
- Hypertension, diabetes, obesity, hyperlipidemia, and ischemic heart disease were common comorbidities.
- Elevated troponin levels were observed in 21.47% of patients.
- All patients exhibited raised D-dimer levels, and varying degrees of Left Ventricular (LV) dysfunction were noted.
Conclusions:
- Cardiac injury and CMPs are frequently observed in patients with COVID-19.
- The findings suggest that cardiac damage should be a key consideration in the management of COVID-19 patients.
- Further research is warranted to elucidate the mechanisms and long-term implications of COVID-19-associated cardiac complications.
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