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Massive cotyledenoid leiomyoma treated with uterine-conserving surgery
William H Parker1, Roderick Turner2, Stanford Schwimer3
1Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, School of Medicine, San Diego, California.
F&S Reports
|July 5, 2021
Summary
A rare cotyledonoid leiomyoma was successfully treated with uterine-conserving surgery. This benign tumor showed no recurrence at 8 years post-operation, demonstrating successful management.
Area of Science:
- Gynecologic Oncology
- Surgical Pathology
Background:
- Cotyledonoid leiomyomas are exceptionally rare benign uterine tumors.
- Massive leiomyomas can present as large abdominal masses, posing diagnostic challenges.
Purpose of the Study:
- To present a case of a massive cotyledonoid leiomyoma.
- To illustrate the successful surgical management using uterine-conserving techniques.
Main Methods:
- A case report detailing a 39-year-old woman with a 28-cm multi-lobulated abdominal mass.
- Diagnosis was aided by magnetic resonance imaging (MRI).
- Surgical intervention involved laparotomy and myomectomy, with intraoperative frozen section analysis.
Main Results:
- The patient underwent successful myomectomy with uterine preservation.
- No recurrence of the cotyledonoid leiomyoma was observed during an 8-year follow-up period.
Conclusions:
- Cotyledonoid leiomyomas are rare, but MRI may suggest their presence preoperatively.
- Frozen section analysis can indicate a benign process.
- Uterine-conserving surgery is a viable and effective treatment option for these tumors.

