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Gallbladder cancer epidemiology, treatment and survival in Southern Finland - a population-based study
Hanna Koppatz1, Sini Takala1, Katriina Peltola2
1Department of Abdominal Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Introduction:
Gallbladder cancer (GBC) is a rare malignancy in Western population with poor prognosis. This study aimed to investigate the trends in GBC incidence, treatment pattern, and survival in Finland.
Methods:
Patients diagnosed with primary GBC in a geographically defined area (Southern Finland Regional Cancer Center) during 2006-2017 were identified.
Results:
Final cohort included 270 patients with GBC. The incidence was 1.32/100,000 persons, and it decreased 6.8 cases per million personyears during the study period. One hundred fifty-one (56%) patients were diagnosed at Stage IV. Fifty-one patients (19%) underwent curative-intent resection with 96% R0-resection rate. The median overall survival was 7.1 months and 5-year overall survival 11.6% for all patients, and 67.7 months and 56.8% after curative-intent resection, respectively. No improvement was noted over time in overall survival in patients with GBC, or in subgroups of different stages of GBC.
Conclusions:
The incidence of GBC is slightly decreasing in Southern Finland, but survival has not improved over time.
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