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Updated: Oct 30, 2025

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
Published on: June 19, 2015
Characterizing the Complexities of Neutrophils with Suppressive Properties
1Department of Medicine, University of Verona, Verona, Italy. marco.cassatella@univr.it.
Abstract:
Several not-yet fully described neutrophil populations exerting either antitumor or suppressive/protumor functions may appear in the circulation of patients with cancer and/or infiltrate tumor tissues. In this issue, Emmons and colleagues provide new information on how complement-dependent "activation" of normal mature neutrophils renders the cells able to inhibit T-cell responsiveness in vitro The data highlight the complexities of understanding the biology of neutrophil-mediated T-cell suppression.See related article by Emmons et al., p. 790.
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