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Updated: Oct 30, 2025

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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
Published on: June 26, 2019
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Abstract:
A liquid biopsy may select patients with metastatic colorectal cancer who are good candidates for additional anti-EGFR therapy after developing resistance to it earlier in their treatment regimen. In a phase II trial, patients who received panitumumab based on an absence of resistance mutations in circulating tumor DNA had a 30% response rate to the anti-EGFR agent.

