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The effects of a multi-disciplinary team on sleep quality assessment in mild-to-moderate Alzheimer's disease patients
Zheli Chen1, Lan Wang2, Ke Chen3
1Associate Chief Physician, Department of Geriatric Psychiatry in Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, China.
Background And Aims:
Sleep disturbances are a severe problem among patients with Alzheimer's disease (AD). By evaluating sleep quality in mild-to-moderate AD patients, this study aimed to assess the effects of multi-disciplinary team (MDT) in reducing the incidence of adverse reactions of AD patients. The reduction in the incidence of adverse reactions to predict multi-disciplinary team (MDT) treatment effects.
Methods And Results:
This study included 60 mild-to-moderate AD patients with sleep problems when hospitalized in Huzhou Third Municipal Hospital. The patients were randomly distributed into two groups, routine and MDT treatments. The cognitive functions, sleep conditions, and psycho-behavioral symptoms were compared between both the groups. Cognitive function declined significantly between pretherapy and follow-up in the routine treatment group (MMSE: t = -7.961, P < 0.001; MoCA: t = -4.672, P < 0.001). There was a significant decline in drowsiness in the MDT group compared to that in the routine treatment group (χ2 = 4.320, P = 0.038). Sleep quality improved significantly during the follow-up in the MDT treatment group (t = 6.098, P < 0.001). The results of the Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) among family caregivers (FCGs) demonstrated that MDT treatment could alleviate caregivers' depression (t = -2.867, P = 0.042), and routine treatment can worsen their anxiety (t = 3.258, P = 0.003).
Conclusion:
The MDT treatment method as an effective and meaningful therapy can help mitigate the suffering of patients with AD and FCGs.
Insights
Multi-disciplinary team (MDT) treatment significantly improved sleep quality and reduced drowsiness in Alzheimer
Area of Science:
- Neurology
- Geriatrics
- Sleep Medicine
Background:
- Sleep disturbances are a significant challenge for patients with Alzheimer's disease (AD).
- Adverse reactions are common in AD patients, impacting their quality of life.
- Evaluating interventions to manage sleep and reduce adverse events is crucial.
Purpose of the Study:
- To assess the effectiveness of multi-disciplinary team (MDT) treatment in improving sleep quality for mild-to-moderate Alzheimer's disease (AD) patients.
- To evaluate the impact of MDT intervention on reducing adverse reactions in AD patients.
- To determine if MDT treatment can predict positive therapeutic effects.
Main Methods:
- A study involving 60 mild-to-moderate AD patients with sleep problems.
- Randomized comparison between routine treatment and multi-disciplinary team (MDT) treatment groups.
- Assessment of cognitive function, sleep quality, and psycho-behavioral symptoms.
Main Results:
- Cognitive function declined in the routine treatment group but improved sleep quality in the MDT group.
- The MDT group showed a significant reduction in drowsiness compared to the routine group.
- MDT treatment alleviated depression in family caregivers, while routine treatment worsened their anxiety.
Conclusions:
- Multi-disciplinary team (MDT) treatment is an effective therapy for Alzheimer's disease (AD) patients.
- MDT intervention improves sleep quality and reduces adverse reactions in AD patients.
- MDT treatment offers meaningful benefits for both AD patients and their family caregivers.
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