Bronchopulmonary dysplasia in extremely premature infant with congenital lobar emphysema: a case report

Bingchun Lin1, Huitao Li1, Chuanzhong Yang2

  • 1Department of Neonatology, Shenzhen Maternity & Child Healthcare Hospital, Cheeloo College of Medicine, Shandong University, Shenzhen, Guangdong, China.

BMC Pediatrics
|July 6, 2021
PubMed

Insights

Congenital lobar emphysema (CLE) is a rare lung condition in premature infants. Early detection with CT scans and prompt surgery are crucial for managing this severe respiratory condition.

Area of Science:

  • Pediatric Pulmonology
  • Neonatology
  • Thoracic Surgery

Background:

  • Congenital lobar emphysema (CLE) is a cystic lung disease causing lobe overinflation and surrounding compression.
  • Symptomatic CLE often necessitates urgent surgical intervention.
  • CLE requires vigilance in extremely premature infants with bronchopulmonary dysplasia (BPD) exhibiting localized emphysema on chest X-rays.

Observation:

  • A case report details a premature infant (27 weeks + 4 days gestational age) presenting with severe respiratory distress at 60 days old.
  • Chest imaging revealed right middle lobe emphysema, confirmed as CLE via histopathology.
  • This highlights a potential complication in high-risk premature infants.

Findings:

  • Premature infants, particularly those with BPD, are at risk for CLE.
  • Localized emphysema on imaging in this population warrants high suspicion for CLE.
  • Histopathological examination confirmed the diagnosis.

Implications:

  • Early recognition of CLE in extremely premature infants is critical.
  • Pulmonary CT scans are essential for timely diagnosis.
  • Prompt surgical intervention can prevent delayed treatment and improve outcomes for infants with CLE.
Abstract

Related Concept Videos

Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
2.2K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.1K
Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.7K
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
61.3K
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
661
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
206