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Viral transport media for COVID-19 testing
Matthew J Mears1,2, Michael J Wallace1,3, Jacob S Yount4
1Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH USA.
Methodsx
|July 6, 2021
Summary
Research labs can produce virus transport media (VTM) using repurposed materials during shortages. This innovation supports mass COVID-19 testing and pandemic response efforts.
Area of Science:
- Virology
- Biotechnology
- Public Health
Background:
- COVID-19 pandemic necessitated rapid diagnostic testing.
- Shortages of commercially available virus transport media (VTM) hindered testing efforts.
- Effective virus detection is critical for controlling infectious disease spread.
Purpose of the Study:
- To present an innovative method for VTM production using repurposed laboratory resources.
- To demonstrate the capacity of university research labs to meet diagnostic media demands during health crises.
- To facilitate large-scale COVID-19 testing through efficient VTM supply.
Main Methods:
- Repurposing existing lab materials, equipment, and personnel.
- Establishing a streamlined VTM production workflow within a university research setting.
- Collaborating across multiple institutions for efficient manufacturing and distribution.
Main Results:
- Successful in-house production of VTM tubes.
- Enabled mass COVID-19 testing by ensuring an adequate supply of VTM.
- Demonstrated the adaptability and resourcefulness of research laboratories.
Conclusions:
- University research labs can effectively produce VTM, mitigating supply chain disruptions.
- This adaptable VTM production model can be implemented during pandemics and future outbreaks.
- In-house VTM production supports rapid public health interventions and disease control.

