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Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients
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Author Spotlight: Deciphering Coagulation Disorders in Traumatic Brain Injury Patients

Published on: August 4, 2023

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Lessons learnt from COVID-19 coagulopathy

Jecko Thachil1

  • 1Department of Haematology Manchester University Hospitals Manchester UK.

Ejhaem
|July 6, 2021
PubMed

Insights

COVID-19 coagulopathy highlights the need for better understanding of blood clotting disorders. Future research should focus on specific markers and funding for hemostasis and thrombosis studies.

Area of Science:

  • Hematology
  • Infectious Diseases
  • Pathology

Background:

  • The COVID-19 pandemic revealed significant challenges in managing infectious diseases.
  • Coagulopathy emerged as a common complication during the pandemic, necessitating a deeper understanding.

Purpose of the Study:

  • To summarize lessons learned from COVID-19-associated coagulopathy.
  • To propose future clinical and research strategies for managing bleeding and clotting disorders.

Main Methods:

  • Review of early pandemic observations on COVID-19 coagulopathy.
  • Synthesis of clinical and research perspectives on hemostasis and thrombosis.

Main Results:

  • COVID-19 coagulopathy underscores the importance of differentiating local versus systemic clotting.
  • Effective use of D-dimers and identification of platelet activation markers are crucial.
  • Re-evaluation of fibrinogen's role, lupus anticoagulant, heparin-induced thrombocytopenia, and disseminated intravascular coagulation is needed.

Conclusions:

  • Further research and funding are essential for advancing hemostasis and thrombosis understanding.
  • Clinical strategies for managing COVID-19-related coagulopathy require refinement based on new insights.

Keywords:
COVID‐19D‐dimercoagulopathyfibrinogenplateletsthrombocytopenia

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