Related Experiment Video
Updated: Oct 29, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
The need for future coronary access following surgical or transcatheter aortic valve replacement
James B Hermiller1, Candace L Gunnarsson2, Michael P Ryan3
1Deptartment of Cardiology, Ascension St. Vincent's Heart Center of Indiana, Indianapolis, Indiana, USA.
Insights
A significant percentage of Medicare patients require coronary access after aortic valve replacement (AVR), particularly those undergoing transcatheter AVR with prior percutaneous coronary intervention or coronary artery disease. This need may grow as AVR expands to younger populations.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Services Research
Background:
- Transcatheter aortic valve replacement (TAVR) indications are expanding to younger, lower-risk patients.
- This expansion raises questions about future coronary access needs post-aortic valve replacement (AVR).
- Understanding long-term coronary access requirements is crucial for patient management.
Purpose of the Study:
- To estimate the percentage of Medicare patients needing coronary access after AVR.
- To analyze coronary access needs based on AVR type (SAVR vs. TAVR) and patient history (PCI, CAD).
Main Methods:
- Retrospective analysis of Medicare patients (<80 years) undergoing AVR (2011-2018).
- Time-to-event analyses using Cox hazard models to predict coronary access risk up to 7 years.
- Adjustments for age, sex, race, region, comorbidity, concomitant CABG, and smoking.
Main Results:
- An estimated 2.5% of patients needed coronary access at 1 year, rising to 17% by 7 years post-AVR.
- For TAVR patients with prior PCI, 28% required coronary access within 4.5 years.
- TAVR patients with coronary artery disease (CAD) had a 22% rate of coronary access by 3 years, versus 7% without CAD.
Conclusions:
- Coronary access is necessary for a substantial proportion of AVR patients, especially TAVR recipients with prior PCI or CAD.
- The demand for coronary access is projected to increase with TAVR's use in younger, longer-living populations.
- Future healthcare planning should consider the growing need for post-AVR coronary interventions.
Abstract:
The aim of the study was to estimate the percentage of Medicare patients needing coronary access for percutaneous coronary intervention (PCI) or coronary angiography following aortic valve replacement (AVR). Indications for TAVR have expanded to include younger and low-risk patients, raising the question of coronary access for future procedures. Medicare patients <80 years old with an AVR between 2011 and 2018 were included. Time-to-event analyses were conducted using Cox hazard models to estimate risk of coronary access up to 7 years after AVR. Model adjustments included age, sex, race, region, comorbidity, concomitant CABG, and smoking. A total of 13,469 Medicare patients (mean age 70.6) met inclusion criteria. Models estimated that 2.5% of patients at 1-year post-index and 17% at over 7 years would need coronary access. For patients who had SAVR (with or without CABG), estimates for coronary access were similar and over 15% after 6.5 years. For TAVR patients, with a previous PCI, 28% at 4.5 years required coronary access, which was higher than TAVR patients without a previous PCI. SAVR patients with and without CAD at baseline were similar; however, TAVR patients with CAD had a 22% rate of coronary access versus 7% for those without at 3 years. Approximately half of patients who needed coronary access returned to the same hospital as their initial AVR. Coronary access is required in a substantial portion of AVR patients especially those with PCI or a history of CAD undergoing TAVR. The need for coronary access may increase as transcatheter AVR becomes accessible to younger patients with a longer life expectancy.
More Related Videos
Related Concept Videos
Aneurysm IV: Nursing Management
Aortic Regurgitation III: Medical Management
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization IV: Nursing Management
Coronary Artery Disease V: Interprofessional Care
Cardiac Catheterization I: Pre-Procedure Overview

