The need for future coronary access following surgical or transcatheter aortic valve replacement

James B Hermiller1, Candace L Gunnarsson2, Michael P Ryan3

  • 1Deptartment of Cardiology, Ascension St. Vincent's Heart Center of Indiana, Indianapolis, Indiana, USA.

Insights

A significant percentage of Medicare patients require coronary access after aortic valve replacement (AVR), particularly those undergoing transcatheter AVR with prior percutaneous coronary intervention or coronary artery disease. This need may grow as AVR expands to younger populations.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Health Services Research

Background:

  • Transcatheter aortic valve replacement (TAVR) indications are expanding to younger, lower-risk patients.
  • This expansion raises questions about future coronary access needs post-aortic valve replacement (AVR).
  • Understanding long-term coronary access requirements is crucial for patient management.

Purpose of the Study:

  • To estimate the percentage of Medicare patients needing coronary access after AVR.
  • To analyze coronary access needs based on AVR type (SAVR vs. TAVR) and patient history (PCI, CAD).

Main Methods:

  • Retrospective analysis of Medicare patients (<80 years) undergoing AVR (2011-2018).
  • Time-to-event analyses using Cox hazard models to predict coronary access risk up to 7 years.
  • Adjustments for age, sex, race, region, comorbidity, concomitant CABG, and smoking.

Main Results:

  • An estimated 2.5% of patients needed coronary access at 1 year, rising to 17% by 7 years post-AVR.
  • For TAVR patients with prior PCI, 28% required coronary access within 4.5 years.
  • TAVR patients with coronary artery disease (CAD) had a 22% rate of coronary access by 3 years, versus 7% without CAD.

Conclusions:

  • Coronary access is necessary for a substantial proportion of AVR patients, especially TAVR recipients with prior PCI or CAD.
  • The demand for coronary access is projected to increase with TAVR's use in younger, longer-living populations.
  • Future healthcare planning should consider the growing need for post-AVR coronary interventions.

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