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Expression of Transgenes in Native Bladder Urothelium Using Adenovirus-Mediated Transduction
Published on: October 6, 2022
[Viral infections in urology]
G Magistro1, A Pilatz2, P Schneede3
1Urologische Klinik und Poliklinik der Universität München, Ludwig-Maximilians-Universität München, München, Deutschland.
Viral infections significantly impact urology, affecting the genitourinary tract and reproduction. Vaccination is crucial for preventing viral diseases in urology patients, especially those undergoing transplantation.
Area of Science:
- Urology
- Infectious Diseases
- Vaccinology
Background:
- The COVID-19 pandemic highlighted the profound impact of infectious diseases on healthcare systems.
- Viral infections are frequently encountered in urological practice, affecting various aspects of patient health.
Purpose of the Study:
- To review viral infections relevant to urology.
- To emphasize the role of vaccination in preventing viral diseases within urology.
Main Methods:
- A selective literature search was conducted.
- Key search terms included "COVID and urology," "urogenital viral infections," "viral urological infections in transplant medicine," and "vaccination prevention of viral diseases."
Main Results:
- Coronaviruses (SARS, MERS, SARS-CoV-2) have caused significant epidemics.
- Numerous viruses detected in ejaculate can cause urogenital infections and impact reproduction (e.g., mumps, enteroviruses, Zika virus).
- Viral infections are common in kidney transplant recipients, underscoring the need for prevention.
Conclusions:
- The genitourinary tract is frequently affected by viruses via viremia or reactivation in immunosuppressed patients.
- Immunomodulation and vaccination prophylaxis are key strategies in managing viral infections in urology.
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