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Updated: Oct 29, 2025
Large-Animal Model of Donation after Circulatory Death and Normothermic Regional Perfusion for Cardiac Assessment
Published on: May 10, 2022
[Donation in the Cardiology Hospital No. 34]
Dilcia Gabriela Alavez-Maldonado1, Gabriel Alejandro Gutiérrez-Beltrán1, Víctor Javier Quezada-Elvira1
1Instituto Mexicano del Seguro Social, Centro Médico Nacional del Noreste, Hospital de Cardiología No. 34, Coordinación de Donación de Órganos y Tejidos. Monterrey, Nuevo León, México.
Insights
This study analyzed organ donation experiences at a Mexican hospital, finding that donation acceptance rates were 39.5%. Factors like the year, month, and time of day influenced successful family consent for organ donation.
Area of Science:
- Medical Science
- Public Health
- Transplantation Medicine
Background:
- Chronic degenerative diseases pose a significant challenge to Mexico's healthcare system.
- Organ and tissue donation and transplantation are key therapeutic strategies.
- This study focuses on a specific hospital's donation program to identify areas for improvement.
Purpose of the Study:
- To analyze the organ donation program's experience at Hospital de Cardiología No. 34 in Monterrey, Mexico.
- To identify opportunities for enhancing the donation program's effectiveness.
- To contribute to the understanding of donation program dynamics in a clinical setting.
Main Methods:
- An observational, cross-sectional, and retrospective study design was employed.
- The study included analysis of deaths and conducted interviews with families.
- Statistical significance was set at p < 0.05 for all analyses.
Main Results:
- Out of 1947 deaths, 210 family interviews were conducted, with 39.5% consenting to donation and 60.5% refusing.
- Effective donation rates increased significantly with the year (p=0.010) and were higher in the second half of the year (p=0.037).
- The morning shift was significantly more successful for obtaining family consent (p=0.012).
Conclusions:
- Analyzing donation program experiences is crucial for promoting organ donation.
- Identifying key factors influencing family consent can optimize donation program strategies.
- Further research is needed to enhance and encourage organ donation practices.
Background:
Chronic degenerative diseases have become a challenge for the Mexican health system. Faced with this problem, health institutions have focused on the therapeutic potential of organ and tissue donation and transplantation.
Objective:
To analyze the experience of the donation program and to identify areas of opportunity at the Hospital de Cardiología No. 34 (Hospital of Cardiology Number 34), in Monterrey, Nuevo León, Mexico.
Material And Methods:
Observational, cross-sectional, and retrospective study. The study population was made up by deaths and successful interviews. Only groupings with values of p < 0.05 were considered statistically significant.
Results:
A global of 1947 deaths were registered and a total of 210 interviews were carried out; 83 (39.5%) family members accepted to donate and 127 (60.5%) refused to donate. Only 3 associations between variables had significant statistical value. The year was an important determinant in the increase in effective donations (p = 0.010), and so was the month of the year (p = 0.037), obtaining more positive interviews in the second half of the year; finally, the shift also contributed to the family response (p = 0.012), with the morning shift being the best shift to conduct a successful family interview.
Conclusions:
It is imperative to conduct studies that analyze and describe the experience of donation programs to promote and encourage the value of donation.
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