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Updated: Oct 29, 2025

Atom Transfer Radical Polymerization of Functionalized Vinyl Monomers Using Perylene as a Visible Light Photocatalyst
Published on: April 22, 2016
Dearomatization through Photoredox Hydroarylation: Discovery of a Radical-Polar Crossover Strategy
Kelly A McDaniel1, Nathan T Jui1
1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.
Abstract:
Indole dearomatization has been achieved via radical hydroarylation. Under mild photoredox conditions, a range of indole derivatives undergo hydroarylation to form 2-arylindoline products. Mechanistically, radical termination occurs primarily via stepwise reduction/protonation, with a small contribution from concerted hydrogen atom transfer. This mechanistic understanding prompted the extension of this reactivity to benzenoid dearomatization. This work formed the foundation of our program, which utilizes reductive radical-polar crossover to drive highly selective dearomatization pathways.
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