Related Experiment Video
Updated: Oct 29, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
The clinical characteristics of pediatric coronavirus disease 2019 in 2020 in Japan
Tomohiro Katsuta1,2, Naoki Shimizu1,2, Kenji Okada1,3
1The Committee on Immunization and Infectious Diseases, Japan Pediatric Society, Tokyo, Japan.
Insights
COVID-19 in children typically presents with mild or no symptoms. Controlling household transmission is key, as school closures had minimal impact on preventing pediatric COVID-19 spread.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- The COVID-19 pandemic impacted all age groups, with children generally experiencing milder symptoms than adults.
- This study is the first nationwide Japanese investigation into pediatric COVID-19 cases, including asymptomatic and mild presentations.
Purpose of the Study:
- To analyze the epidemiological and clinical characteristics of pediatric COVID-19 cases in Japan.
- To investigate COVID-19 transmission patterns among children.
- To assess the impact of nationwide school closures on pediatric COVID-19 transmission.
Main Methods:
- Analysis of 840 pediatric (<16 years) COVID-19 cases reported in Japan (February-December 2020).
- Utilized a dedicated database maintained by the Japan Pediatric Society.
- Examined epidemiological data, clinical characteristics, and transmission routes.
Main Results:
- Nearly half (47.7%) of pediatric cases were asymptomatic; most others had mild symptoms.
- 84.0% of cases were afebrile upon initial assessment.
- Household transmission was the predominant route (72.5% exposed to infected members), unaffected by school closures.
Conclusions:
- Pediatric COVID-19 symptoms are generally less severe than adult cases.
- Nationwide school closures demonstrated a limited effect on reducing COVID-19 transmission among children.
- Preventing household transmission from adults is crucial for protecting children from COVID-19.
Background:
The COVID-19 pandemic has affected the lives of people of all ages. Most reports on pediatric cases suggest that children experience fewer and milder symptoms than do adults. This is the first nationwide study in Japan focusing on pediatric cases reported by pediatricians, including cases with no or mild symptoms.
Methods:
We analyzed the epidemiological and clinical characteristics and transmission patterns of 840 pediatric (<16 years old) COVID-19 cases reported between February and December 2020 in Japan, using a dedicated database which was maintained voluntarily by members of the Japan Pediatric Society.
Results:
Almost half of the patients (47.7%) were asymptomatic, while most of the others presented mild symptoms. At the time of admission or first outpatient clinic visit, 84.0% of the cases were afebrile (<37.5°C). In total, 609 cases (72.5%) were exposed to COVID-19-positive household members. We analyzed the influence of nationwide school closures that were introduced in March 2020 on COVID-19 transmission routes among children in Japan. Transmission within households occurred most frequently, with no significant difference between the periods before and after declaring nationwide school closures (70.9% and 74.5%, respectively).
Conclusions:
COVID-19 symptoms in children are less severe than those in adults. School closure appeared to have a limited effect on transmission. Controlling household transmission from adult family members is the most important measure for prevention of COVID-19 among children.
More Related Videos
09:37Detection of Polyfunctional T Cells in Children Vaccinated with Japanese Encephalitis Vaccine via the Flow Cytometry Technique
Published on: September 23, 2022
12:20Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Distribution
Pharmacokinetics in Pediatric Patients: Drug Excretion
Pharmacokinetics in Pediatric Patients: Drug Metabolism
COPD: Pathogenesis and Clinical Features
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
Principles of Disease Surveillance