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Related Concept Videos

Electroconvulsive Therapy01:30

Electroconvulsive Therapy

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
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Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
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Fever as a Side Effect after Electroconvulsive Therapy.

Young Tak Jo1, Jungsun Lee1, Yeon Ho Joo1

  • 1Department of Psychiatry, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Neuropsychobiology
|July 7, 2021
PubMed
Summary

Fever after electroconvulsive therapy (ECT) affects 8.8% of patients, often occurring with longer seizures and postictal delirium. This study suggests post-ECT fever is a common side effect requiring attention.

Keywords:
Electroconvulsive therapyFeverSide effect

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Area of Science:

  • Psychiatry
  • Neurology

Background:

  • Electroconvulsive therapy (ECT) is a vital non-pharmacological psychiatric treatment.
  • Post-ECT fever is an infrequently reported adverse event.

Purpose of the Study:

  • To investigate the incidence and characteristics of fever following electroconvulsive therapy (ECT).
  • To identify factors associated with post-ECT fever.

Main Methods:

  • Retrospective review of medical records for patients undergoing ECT.
  • Comparison of variables between ECT sessions with and without fever.

Main Results:

  • Fever occurred in 8.8% of patients (1.5% of sessions).
  • Fever group showed higher female-to-male ratio and more total ECT sessions.
  • Fever sessions correlated with longer seizure duration and increased postictal delirium.

Conclusions:

  • Fever following ECT is a common side effect, observed in 8.8% of patients.
  • Fever sessions were associated with higher white blood cell counts and lower quetiapine use.
  • Longer seizure duration and postictal delirium are linked to post-ECT fever.