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Author Spotlight: Exercise Test for Evaluation of the Functional Efficacy of the Pig Cardiovascular System
Published on: May 12, 2023
Safety and Efficacy of Scientist Led Exercise Stress Testing for Arrhythmia Provocation and Chronotropic Competence
Mark Whitman1, Adelle S D'souza2, Carly Jenkins3
1Cardiac Investigations Unit, Logan Hospital, Meadowbrook, Queensland, Australia; School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, Australia.
Insights
Non-physician-led exercise stress testing (EST) is safe and effective for diagnosing arrhythmias and other cardiac conditions. Cardiac scientists can perform these tests, achieving results comparable to cardiologists, with excellent agreement.
Area of Science:
- Cardiology
- Clinical Electrophysiology
Background:
- Non-physician-led exercise stress testing (EST) is widely used for coronary artery disease investigation.
- Current safety guidelines do not explicitly cover EST for arrhythmia provocation or chronotropic assessment.
Purpose of the Study:
- To evaluate the safety and efficacy of non-physician-led EST for suspected arrhythmias.
- To assess chronotropic competence, long QT syndrome, and accessory pathway conduction (APC) using non-physician-led EST.
Main Methods:
- 486 patients underwent non-physician-led EST for suspected arrhythmias or related conditions.
- Tests were conducted by trained cardiac scientists and over-read by consultant cardiologists.
- Patients were followed for an average of 1.8 years.
Main Results:
- No significant adverse events (myocardial infarction, hemodynamically compromising arrhythmias, syncope) occurred during testing.
- 98.4% interobserver agreement between cardiologists and cardiac scientists indicated excellent concordance.
- 12.1% of patients required subsequent interventions like pacemakers or ablation.
Conclusions:
- Non-physician-led EST, performed by cardiac scientists, is a safe and effective diagnostic tool.
- This approach yields diagnostic interpretations equivalent to those of consultant cardiologists.
- EST can be safely extended for investigating arrhythmias, chronotropic issues, and accessory pathways.
Abstract:
For many years, non physician led exercise stress testing performed for the investigation of coronary artery disease has been endorsed by many cardiovascular (CV) societies and associations around the world. The safety guidelines don't currently include the performing of these tests for arrhythmia provocation or chronotropic assessment. Therefore, the aim of this study was to assess the safety and efficacy of non physician led EST performed for suspected arrhythmias, chronotropic competence, long QT, and accessory pathway conduction (APC) assessment. A total of 486 patients performed an exercise stress test for either of the above suspected conditions and were followed for 1.8 years ± 1.5 years. Tests were performed by a trained cardiac scientist with all reports over-read by a consultant Cardiologist. There were no significant adverse events (myocardial infarction, arrhythmia causing hemodynamic compromise or syncope) at time of testing. A total of 12.1% of patients required further follow up consisting of either a cardiac pacemaker, an implantable cardioverter defibrillator, radiofrequency ablation, Direct-Current cardioversion or a change in medications. Interobserver agreement between the Cardiologist and cardiac scientist was 98.4% indicating excellent agreement. In conclusion, the present study demonstrates that cardiac scientists can safely perform non physician led EST for the investigation of suspected arrhythmias, chronotropic competence, long QT, and APC assessment with a diagnostic interpretation equivalent to that of a consultant Cardiologist.
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