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Severe diarrhoea due to use of P2Y12 inhibitor ticagrelor: a rarely reported adverse event

Khalid Rashid1, Muhammad Aamir Waheed2, Hafeez Ur Rehman3

  • 1Department of General Medicine, Northampton General Hospital NHS Trust, Northampton, UK Khalidrashid93@gmail.com.

BMJ Case Reports
|July 8, 2021
PubMed

Insights

Diarrhea is a potential side effect of ticagrelor, an antiplatelet medication used after percutaneous coronary intervention. This case report highlights that ticagrelor-induced diarrhea resolved after switching to an alternative antiplatelet agent.

Area of Science:

  • Cardiology
  • Pharmacology
  • Gastroenterology

Background:

  • Dual antiplatelet therapy (DAPT) with aspirin and ticagrelor is standard for acute coronary syndrome (ACS) patients post-percutaneous coronary intervention (PCI).
  • While effective, DAPT can cause adverse effects, including gastrointestinal issues.
  • Diarrhea is a less commonly reported side effect of ticagrelor.

Keywords:
cardiovascular systemcontraindications and precautionsischaemic heart disease

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