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Updated: Oct 29, 2025

Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
Published on: February 2, 2024
Antenatal magnesium sulfate to prevent cerebral palsy
Amy K Keir1,2,3, Emily Shepherd4, Sarah McIntyre5
1SAHMRI Women and Kids, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia amy.keir@adelaide.edu.au.
Abstract:
Magnesium sulfate given to women before birth at <30 weeks' gestation reduces the risk of cerebral palsy in their children. Our study aimed to assess the impact of a local quality improvement programme, primarily using plan-do-study-act cycles, to increase the use of antenatal magnesium sulfate. After implementing our quality improvement programme, an average of 86% of babies delivered at <30 weeks' gestation were exposed to antenatal magnesium sulfate compared with a historical baseline rate of 63%. Our study strengthens the case for embedding quality improvement programmes in maternal perinatal care to reduce the impact of cerebral palsy on families and society.
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