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An Unusual Hodgkin's Lymphoma Journey: Cardiac Tamponade, Primary Refractoriness, Immune Thrombocytopenia, and

Juan Jose Chango Azanza1, James Vredenburgh2

  • 1Internal Medicine, University of Connecticut School of Medicine, Farmington, USA.

Cureus
|July 8, 2021
PubMed

Hodgkin's lymphoma (HL) is a lymphoid neoplasm in which malignant Hodgkin or Reed-Sternberg cells are present in tissues mixed with heterogeneous non-malignant inflammatory cells. Pericardial effusion (PEEF) in HL is rare. Furthermore, hemodynamically significant effusions causing cardiac tamponade (CTp) are exceedingly uncommon. CTp as the initial presentation of HL is extremely rare. We describe the case of a 21-year-old man who presented with CTp requiring pericardiocentesis. On further workup, he was found to have a large mediastinal mass with a biopsy consistent with classic HL. His clinical course was complicated by the development of immune thrombocytopenia (ITP) and post-traumatic stress disorder (PTSD).

Keywords:
cardiac tamponadehodgkin lymphomaimmune thrombocytopeniapost-traumatic stress disorder

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