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Updated: Oct 29, 2025

Mass Cytometry Analysis of Systemic and Local Immune Responses in Hepatocellular Carcinoma
Published on: April 25, 2025
Current Perspectives on B Lymphocytes in the Immunobiology of Hepatocellular Carcinoma
Miaomiao Qin1, Danping Wang2, Yijiao Fang3
1Department of Anesthesiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Abstract:
Immune cells infiltrating tumors are capable of significantly impacting carcinogenesis through cancer promotion and anticancer responses. There are many aspects of hepatocellular carcinoma (HCC) related T lymphocytes that are undergoing extensive studies, whereas the effect exerted by B lymphocytes remains a less researched area. In this study, the latest research on the effect of B lymphocytes as they infiltrate tumors in relation to HCC is presented. Their prognosis-related importance is analyzed, along with their function in the tumor microenvironment (TME), as well as the way that B cell biology can be employed to help create a B cell therapy strategy for HCC.
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